PRT-060318 |CAS:1194961-19-7 Probechem Biochemicals

Chemical Structure : PRT-060318

CAS No.: 1194961-19-7

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PRT-060318 (PRT318)

货号: PC-43303Not For Human Use, Lab Use Only.

PRT-060318 is a potent and selective Syk inhibitor with IC50 of 4 nM.

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10 mg	￥1380	In stock
25 mg	￥2180	In stock
50 mg	￥3680	In stock
100 mg		Get quote

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生物&药学活性

PRT-060318 is a potent and selective Syk inhibitor with IC50 of 4 nM.
PRT-060318 shows selectivity in a broad panel of kinase enzyme assays.
PRT-060318 completely inhibits Heparin-induced thrombocytopenia (HIT) immune complex-induced aggregation of both human and transgenic HIT mouse platelet.

物理化学性质&存储条件

分子量	340.4228
分子式	C18H24N6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	H2O: 5.6 mg/mL
Chemical Name/SMILES	5-Pyrimidinecarboxamide, 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(3-methylphenyl)amino]-

参考文献

1. Reilly MP, et al. Blood. 2011 Feb 17;117(7):2241-6.

2. Hoellenriegel J, et al. Leukemia. 2012 Jul;26(7):1576-83.

3. Andre P, et al. Blood. 2011 Nov 3;118(18):5000-10.

PRT-060318 (PRT318)

生物&药学活性

物理化学性质&存储条件

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PRT-060318 (PRT318)

生物&药学活性

物理化学性质&存储条件

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