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PR280

Chemical Structure : PR280

CAS No.:

PR280 (PR-280)

货号: PC-26797Not For Human Use, Lab Use Only.

PR280 is a potent small molecule inhibitor of dihydroceramide desaturase 1 (Des1) with IC50 of 700 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PR280 is a potent small molecule inhibitor of dihydroceramide desaturase 1 (Des1) with IC50 of 700 nM.

物理化学性质&存储条件

分子量 451.69
分子式 C27H49NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-((1R,2S)-1,3-dihydroxy-1-(3-oxo-2-tridecylcycloprop-1-en-1-yl)propan-2-yl)octanamide

参考文献

1. Pablo Rivero, et al. Bioorg Chem. 2024 Apr:145:107233.

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