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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-PPAR-PPARα agonist A190
PPARα agonist A190

Chemical Structure : PPARα agonist A190

CAS No.: 2376590-40-6

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PPARα agonist A190 (Compound 4u)

货号: PC-24032Not For Human Use, Lab Use Only.

PPARα agonist A190 is a highly selective and potent nonfibrate PPARα agonist with EC50 of 37 nM (hPPARα), exhibits >2,700-fold selectivity for PPARα over other PPAR isoforms.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PPARα agonist A190 is a highly selective and potent nonfibrate PPARα agonist with EC50 of 37 nM (hPPARα), exhibits >2,700-fold selectivity for PPARα over other PPAR isoforms.

物理化学性质&存储条件

分子量 365.40
分子式 C22H20FNO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-((4-((4-fluorobenzyl)oxy)-3-methylbenzyl)amino)benzoic acid

参考文献

1. Xiaozheng Dou, et al. J Med Chem. 2020 Mar 26;63(6):2854-2876.

2. Pangeni R, et al. Mol Pharm. 2025 Jan 29. doi: 10.1021/acs.molpharmaceut.4c01374.

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