PP1 inhibitor C31 |CAS 752216-12-9 Probechem Biochemicals

Chemical Structure : PP1 inhibitor C31

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PP1 inhibitor C31

货号: PC-35687Not For Human Use, Lab Use Only.

PP1 inhibitor C31 is a 1E7-03 analog and protein phosphatase 1 (PP1) targeting small molecule with Kd of 1.88 uM, inhibits Ebola virus (EBOV) transcription and replication.

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200 mg		Get quote
1 g		Get quote

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生物&药学活性

PP1 inhibitor C31 is a 1E7-03 analog and protein phosphatase 1 (PP1) targeting small molecule with Kd of 1.88 uM, inhibits Ebola virus (EBOV) transcription and replication.
PP1 inhibitor C31 binds to the PP1 C-terminal groove in vitro and increased VP30 phosphorylation in cultured cells, also inhibits EBOV minigenome.
PP1 inhibitor C31 is a novel PP1-targeting EBOV inhibitor with improved pharmacological properties.

物理化学性质&存储条件

分子量	475.501
分子式	C26H25N3O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-oxo-1-ureidopropan-2-yl (E)-3-(3,4-dimethoxybenzylidene)-2,3-dihydro-1H-cyclopenta[b]quinoline-9-carboxylate

参考文献

1. Ammosova T, et al. J Infect Dis. 2018 Aug 28. doi: 10.1093/infdis/jiy422.