PNU 96415E |CAS:170856-41-4 Probechem Biochemicals

Chemical Structure : PNU 96415E

加入收藏

PNU 96415E (PNU-96415E;PNU96415E )

货号: PC-60613Not For Human Use, Lab Use Only.

A potential antipsychotic agent that binds selectively to D4 and 5-HT2A receptors with Ki of 3.0 and 5.8 nM, respectively.

规格	价格	库存	数量
25 mg		Get quote
100 mg		Get quote
250 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

A potential antipsychotic agent that binds selectively to D4 and 5-HT2A receptors with Ki of 3.0 and 5.8 nM, respectively; has relatively lower affinities for D1, D2, D3, 5-HT1A and α2 receptors (Ki=200-400 nM), and no affitnity for muscarinic receptors; inhibits exploratory locomotor activity in mice and rats, and antagonizes d-amphetamine-induced locomotor stimulation in rats; also selectively inhibits GBM neural stem cells (GNS) growth and promotes differentiation of normal neural stem cells.

物理化学性质&存储条件

分子量	413.358
分子式	C21H27Cl2FN2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(±)-1-(4-Fluorophenyl)-4-[2-(isochroman-1-yl)ethyl]piperazine dihydrochloride

参考文献

1. Tang AH, et al. J Pharmacol Exp Ther. 1997 Apr;281(1):440-7.

2. Dolma S, et al. Cancer Cell. 2016 Jun 13;29(6):859-873.

3. Goudie AJ, et al. Behav Pharmacol. 1998 Dec;9(8):699-710.

PNU 96415E (PNU-96415E;PNU96415E )

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

PNU 96415E (PNU-96415E;PNU96415E )

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.