PNU-112455A |CAS:21886-12-4 Probechem Biochemicals

Chemical Structure : PNU-112455A

CAS No.: 21886-12-4

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PNU-112455A (PNU112455A)

货号: PC-62677Not For Human Use, Lab Use Only.

PNU-112455A is an ATP-competitive CDK2/5 inhibitor with Ki of 2 uM and 2 uM for cdk2·GST-cyclin E and cdk5·GST-p25 respectively, shows no activity against c-Met, IGR-1R, and ERK2.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

PNU-112455A is an ATP-competitive CDK2/5 inhibitor with Ki of 2 uM and 2 uM for cdk2·GST-cyclin E and cdk5·GST-p25 respectively, shows no activity against c-Met, IGR-1R, and ERK2.

物理化学性质&存储条件

分子量	301.749
分子式	C10H12ClN5O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N4-(6-aminopyrimidin-4-yl)-sulfanilamide hydrochloride

参考文献

1. Clare PM, et al. J Biol Chem. 2001 Dec 21;276(51):48292-9.

2. Monaco EA 3rd, et al. Biochem Pharmacol. 2004 May 15;67(10):1947-64.

PNU-112455A (PNU112455A)

生物&药学活性

物理化学性质&存储条件

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PNU-112455A (PNU112455A)

生物&药学活性

物理化学性质&存储条件

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