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PLpro-IN-6

Chemical Structure : PLpro-IN-6

CAS No.: 1093070-14-4

PLpro-IN-6 (SARS-CoV PLpro-IN-6)

货号: PC-45340Not For Human Use, Lab Use Only.

PLpro-IN-6 is a potent, noncovalent SARS-CoV papain-like protease (PLpro) inhibitor with IC50 of 2.6 uM.

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2 mg ¥1980 In stock
5 mg ¥3280 In stock
10 mg ¥5280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PLpro-IN-6 is a potent, noncovalent SARS-CoV papain-like protease (PLpro) inhibitor with IC50 of 2.6 uM.
PLpro-IN-6 inhibits SARS-CoV viral replication in Vero E6 cells with EC50 of 13.1 uM, has no associated cytotoxicity and no inhibition for host DUBs.

物理化学性质&存储条件

分子量 346.4223
分子式 C22H22N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 42 mg/mL

Chemical Name/SMILES

Benzamide, 5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]-

参考文献

1. Ratia K, et al. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16119-24.

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