PLK1-IN-14f |CAS:2041789-49-3 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Polo-like Kinase (PLK)-PLK1-IN-14f

Chemical Structure : PLK1-IN-14f

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PLK1-IN-14f

货号: PC-62790Not For Human Use, Lab Use Only.

PLK1-IN-14f is a potent PLK1 inhibitor, exhibits potent activity against a panel cancer cell lines with GI50 values ranging from 0.30 to 0.60 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PLK1-IN-14f is a potent PLK1 inhibitor, exhibits potent activity against a panel cancer cell lines with GI50 values ranging from 0.30 to 0.60 uM.
PLK1-IN-14f causes cell-cycle arrest at the G2/M phase and induced apoptosis by targeting CDC25C and Mcl-1 proteins in A2780 ovarian cells.

物理化学性质&存储条件

分子量	393.454
分子式	C19H23NO6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N-(4-ethoxyphenyl)-2-(2,4,6-trimethoxyphenyl)ethene-1-sulfonamide

参考文献

1. Long Y, et al. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5674-5678.

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PLK1-IN-14f

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PLK1-IN-14f

生物&药学活性

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