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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-c-Myc-PKUMDL-YC-1205
PKUMDL-YC-1205

Chemical Structure : PKUMDL-YC-1205

CAS No.: 132388-59-1

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PKUMDL-YC-1205 (c-Myc bHLH-LZ domain inhibitor)

货号: PC-72260Not For Human Use, Lab Use Only.

PKUMDL-YC-1205 is a specific small molecule that can specifically bind to the disordered bHLH-LZ domain of c-Myc (SPR Kd=18 uM).

规格 价格 库存 数量
10 mg ￥1880 In stock
25 mg ￥2980 In stock
50 mg ￥4880 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PKUMDL-YC-1205 is a specific small molecule that can specifically bind to the disordered bHLH-LZ domain of c-Myc (SPR Kd=18 uM).
PKUMDL-YC-1205 abrogates cell proliferation of HL-60 cells with IC50 of 40 uM, blocks the interaction between c-Myc370–409 and Max.

物理化学性质&存储条件

分子量 596.683
分子式 C38H32N2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N4-trityl-L-asparagine

参考文献

1. Chen Yu, et al. Sci Rep. 2016 Mar 2;6:22298.

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