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首页-小分子抑制剂&激动剂-Others-PHGDH-PKUMDL-WQ-2201
PKUMDL-WQ-2201

Chemical Structure : PKUMDL-WQ-2201

CAS No.: 592474-91-4

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PKUMDL-WQ-2201 (WQ-2201)

货号: PC-72880Not For Human Use, Lab Use Only.

PKUMDL-WQ-2201 is a potent, selective, allosteric inhibitor of PHGDH, binds to allosteric site II.

规格 价格 库存 数量
10 mg ￥1280 In stock
25 mg ￥2180 In stock
50 mg ￥3580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PKUMDL-WQ-2201 is a potent, selective, allosteric inhibitor of PHGDH, binds to allosteric site II.
PKUMDL-WQ-2201 inhibited the serine biosynthesis pathway in cells, exhibited substantial inhibitory effects on MDA-MB-468 xenografts.

物理化学性质&存储条件

分子量 351.805
分子式 C15H14ClN3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-Chloro-4-[5-[(ethylcarbamothioylhydrazinylidene)methyl]furan-2-yl]benzoic acid

参考文献

1. Qian Wang, et al. Cell Chem Biol. 2017 Jan 19;24(1):55-65.

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