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首页-小分子抑制剂&激动剂-Apoptosis-Ferroptosis-PKUMDL-LC-102
PKUMDL-LC-102

Chemical Structure : PKUMDL-LC-102

CAS No.: 22431-06-7

PKUMDL-LC-102

货号: PC-24821Not For Human Use, Lab Use Only.

PKUMDL-LC-102 is a selective, allosteric small molecule GPX4 activator (150% activation at 39.2 μM), shows no activity against COX-1, COX-2, mPGES-1, 5-LOX, LTA4H, 12-LOX, and 15-LOX.

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5 mg ¥1980 In stock
10 mg ¥2980 In stock
25 mg ¥4980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PKUMDL-LC-102 is a selective, allosteric small molecule GPX4 activator (150% activation at 39.2 μM), shows no activity against COX-1, COX-2, mPGES-1, 5-LOX, LTA4H, 12-LOX, and 15-LOX.

物理化学性质&存储条件

分子量 219.20
分子式 C10H9N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-amino-3a,8a-dihydroxy-3a,8a-dihydroindeno[1,2-d]imidazol-8(3H)-one

参考文献

1. Li C, et al. Front Pharmacol. 2018 Oct 3:9:1120.

2. Liu X, et al. J Orthop Translat. 2025 May 7;52:344-359.

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