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首页-小分子抑制剂&激动剂-Apoptosis-MDM2-p53-PK5196
PK5196

Chemical Structure : PK5196

CAS No.: 1370554-91-8

PK5196

货号: PC-25763Not For Human Use, Lab Use Only.

PK5196 is a small molecule p53 Y220C reactivator and p53 Y220C binder (SPR Kd=6.88 uM), effectively increase the thermal stability of p53 Y220C protein.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PK5196 is a small molecule p53 Y220C reactivator and p53 Y220C binder (SPR Kd=6.88 uM), effectively increase the thermal stability of p53 Y220C protein.

物理化学性质&存储条件

分子量 517.46
分子式 C25H32IN3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((4-(diethylamino)piperidin-1-yl)methyl)-6-iodo-4-(3-(phenylamino)prop-1-yn-1-yl)phenol

参考文献

1. Rainer Wilcken, et al. J Am Chem Soc. 2012 Apr 18;134(15):6810-8.

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