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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-GABA Receptor-PK14105
PK14105

Chemical Structure : PK14105

CAS No.: 107257-28-3

PK14105 (PK-14105)

货号: PC-42106Not For Human Use, Lab Use Only.

PK14105 is a potent photoaffinity ligand for the peripheral-type benzodiazepine binding site with Ki of 4 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PK14105 is a potent photoaffinity ligand for the peripheral-type benzodiazepine binding site with Ki of 4 nM.
PK14105 attaches covalently and specifically to all the PBS when cardiac membranes are irradiated with this compound under ultraviolet light.

物理化学性质&存储条件

分子量 381.4002
分子式 C21H20FN3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

3-Isoquinolinecarboxamide, 1-(2-fluoro-5-nitrophenyl)-N-methyl-N-(1-methylpropyl)-

参考文献

1. Doble A, et al. Mol Pharmacol. 1987 Jan;31(1):42-9.

2. Doble A, et al. J Recept Res. 1987;7(1-4):55-70.

3. Skowroński R, et al. Eur J Pharmacol. 1988 Mar 29;148(2):187-93.

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