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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-PITCOIN4
PITCOIN4

Chemical Structure : PITCOIN4

CAS No.:

PITCOIN4

货号: PC-23002Not For Human Use, Lab Use Only.

PITCOIN4 is a potent, highly selective inhibitor of class II alpha PI3K (PI3K-C2α) with IC50 of 56 nM, >100-fold selectivity over PI3K-C2β.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PITCOIN4 is a potent, highly selective inhibitor of class II alpha PI3K (PI3K-C2α) with IC50 of 56 nM, >100-fold selectivity over PI3K-C2β.

物理化学性质&存储条件

分子量 599.73
分子式 C30H29N7O3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(5-(2-Oxo-2-((2-phenylpropan-2-yl)amino)ethyl)thiazol-2-yl)-2-((4-oxo-3-phenethyl-3,4-dihydropteridin-2-yl)thio)acetamide

参考文献

1. Murat Kücükdisli, et al. J Med Chem. 2023 Oct 26;66(20):14278-14302.

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