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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-PITCOIN2
PITCOIN2

Chemical Structure : PITCOIN2

CAS No.: 2397679-77-3

PITCOIN2 (LU-06-006)

货号: PC-20451Not For Human Use, Lab Use Only.

PITCOIN2 (LU-06-006) is a potent selective PI3KC2α inhibitor with IC50 of 126 nM, has selectivity against PI3KC2γ but shows micromolar activity on PI3KC2β.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PITCOIN2 (LU-06-006) is a potent selective PI3KC2α inhibitor with IC50 of 126 nM, has selectivity against PI3KC2γ but shows micromolar activity on PI3KC2β.

物理化学性质&存储条件

分子量 516.59
分子式 C25H20N6O3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-(3-hydroxyphenyl)thiazol-2-yl)-2-((4-oxo-3-phenethyl-3,4-dihydropteridin-2-yl)thio)acetamide

参考文献

1. Lo WT, et al. Nat Chem Biol. 2023 Jan;19(1):18-27.

2. Patent WO2019234237 A1.

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