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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-PITCOIN1
PITCOIN1

Chemical Structure : PITCOIN1

CAS No.: 2397679-87-5

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PITCOIN1

货号: PC-23007Not For Human Use, Lab Use Only.

PITCOIN1 is a potent, highly selective inhibitor of class II alpha PI3K (PI3K-C2α) with IC50 of 100 nM, with no activity against class I and III PI3Ks.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PITCOIN1 is a potent, highly selective inhibitor of class II alpha PI3K (PI3K-C2α) with IC50 of 100 nM, with no activity against class I and III PI3Ks.

物理化学性质&存储条件

分子量 424.50
分子式 C19H16N6O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-((4-Oxo-3-phenethyl-3,4-dihydropteridin-2-yl)thio)-N-(thiazol-2-yl)acetamide

参考文献

1. Murat Kücükdisli, et al. J Med Chem. 2023 Oct 26;66(20):14278-14302.

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