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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-PIK-294
PIK-294

Chemical Structure : PIK-294

CAS No.: 900185-02-6

PIK-294 (PIK294)

货号: PC-42518Not For Human Use, Lab Use Only.

PIK-294 is a highly potent, selective p110δ inhibitor with IC50 of 10 nM, shows 1000-, 49- and 16-fold less potent to PI3Kα/β/γ.

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10 mg ¥880 In stock
25 mg ¥1380 In stock
50 mg ¥2180 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PIK-294 is a highly potent, selective p110δ inhibitor with IC50 of 10 nM, shows 1000-, 49- and 16-fold less potent to PI3Kα/β/γ.

物理化学性质&存储条件

分子量 489.5279
分子式 C28H23N7O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 40 mg/mL

Chemical Name/SMILES

4(3H)-Quinazolinone, 2-[[4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)-

参考文献

1. Knight ZA, et al. Cell. 2006 May 19;125(4):733-47.

2. Martin KJ, et al. PLoS One. 2015 Feb 6;10(2):e0116250.

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