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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-PIK-108
PIK-108

Chemical Structure : PIK-108

CAS No.: 901398-68-3

PIK-108 (PIK108, PIK 108)

货号: PC-21948Not For Human Use, Lab Use Only.

PIK-108 is a potent, selective and allosteric PI3K p110β inhibitor with IC50 of 57 nM, 45-fold selective over PI3Kα (IC50=2600 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PIK-108 is a potent, selective and allosteric PI3K p110β inhibitor with IC50 of 57 nM, 45-fold selective over PI3Kα (IC50=2600 nM).

物理化学性质&存储条件

分子量 364.45
分子式 C22H24N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-Methyl-2-morpholino-8-(1-(phenylamino)ethyl)-4H-chromen-4-one

参考文献

1. Chen JS, et al. Mol Cancer Ther. 2008 Apr;7(4):841-50.

2. Hon WC, et al. Oncogene. 2012 Aug 9;31(32):3655-66.

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