PI5P4Kγ inhibitor 40

Chemical Structure : PI5P4Kγ inhibitor 40

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货号: PC-38270Not For Human Use, Lab Use Only.

PI5P4Kγ inhibitor 40 is a selective, non-ATP-competitive, allosteric inhibitor of PI5P4Kγ with pIC50 of 6.2, does not inhibit PI5P4Kα/β with pIC50<4.6.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

PI5P4Kγ inhibitor 40 is a selective, non-ATP-competitive, allosteric inhibitor of PI5P4Kγ with pIC50 of 6.2, does not inhibit PI5P4Kα/β with pIC50<4.6.

物理化学性质&存储条件

分子量	357.461
分子式	C22H23N5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-isopropylphenyl)-5-methyl-N-(pyridin-2-ylmethyl)-5H-pyrrolo[3,2-d]pyrimidin-4-amine

参考文献

1. Helen K Boffey, et al. J Med Chem. 2022 Feb 11. doi: 10.1021/acs.jmedchem.1c01819.