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首页-小分子抑制剂&激动剂-Others-Other Targets-PI5P4Kγ-IN-1
PI5P4Kγ-IN-1

Chemical Structure : PI5P4Kγ-IN-1

CAS No.: 2419358-87-3

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PI5P4Kγ-IN-1

货号: PC-27758Not For Human Use, Lab Use Only.

PI5P4Kγ-IN-1 is a potent, selective and ATP-competitive chemical probe inhibitor for PI5P4Kγ with Kd of 19 nM and IC50 of 67 nM, effectively inhibits PI5P4Kγ function and activates the mTORC1 signaling pathway in cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PI5P4Kγ-IN-1 is a potent, selective and ATP-competitive chemical probe inhibitor for PI5P4Kγ with Kd of 19 nM and IC50 of 67 nM, effectively inhibits PI5P4Kγ function and activates the mTORC1 signaling pathway in cells.

物理化学性质&存储条件

分子量 332.41
分子式 C20H20N4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

11-(3,6-dihydro-2H-pyran-4-yl)-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-2-amine

参考文献

1. Drewry DH, et al. Curr Res Chem Biol. 2023;3:100036.

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