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PI5P4K inhibitor 30

Chemical Structure : PI5P4K inhibitor 30

CAS No.: 2471969-07-8

PI5P4K inhibitor 30

货号: PC-38274Not For Human Use, Lab Use Only.

PI5P4K inhibitor 30 is a highly selective pan-PI5P4K covalent inhibitor with IC50 of 1.3/9.9 uM against PI5P4Kα/β, inhibits PI5P4Kγ by 22% at 1 uM..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    PI5P4K inhibitor 30 is a highly selective pan-PI5P4K covalent inhibitor with IC50 of 1.3/9.9 uM against PI5P4Kα/β, inhibits PI5P4Kγ by 22% at 1 uM.

    物理化学性质&存储条件

    分子量 545.647
    分子式 C32H31N7O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-4-(4-(dimethylamino)but-2-enamido)-N-(3-((7-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)phenyl)benzamide

    参考文献

    1. Theresa D Manz, et al. ACS Med Chem Lett. 2019 Nov 3;11(3):346-352.

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