PI4KIIIβ inhibitor 7f

Chemical Structure : PI4KIIIβ inhibitor 7f

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货号: PC-22613Not For Human Use, Lab Use Only.

PI4KIIIβ inhibitor 7f is a potent, selective inhibitor of phosphatidylinositol-4-kinase IIIβ (PI4KIIIβ) with IC50 of 16 nM, with no activity for PI4KIIIα (>10 μM).

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

PI4KIIIβ inhibitor 7f is a potent, selective inhibitor of phosphatidylinositol-4-kinase IIIβ (PI4KIIIβ) with IC50 of 16 nM, with no activity for PI4KIIIα (>10 μM).
PI4KIIIβ inhibitor 7f also inhibits the class I and II PI3K superfamilies, which are associated with cancer and immunodeficiency diseases.
PI4KIIIβ inhibitor 7f potently inhibits EV71 replication with IC50 of 4.5 nM.
PI4KIIIβ inhibitor 7f exibits potent antiviral therapy against hRVs or other enteroviruses.

物理化学性质&存储条件

分子量	553.65
分子式	C27H27N3O6S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3,5-dimethoxyphenyl)-N-(5-(4-methoxy-3-(phenylsulfonamido)phenyl)-4-methylthiazol-2-yl)acetamide

参考文献

1. G Vishakantegowda A, et al. RSC Med Chem. 2023 Dec 21;15(2):704-719.