PI4KIIIbeta-IN-10 | PI4KIIIβ inhibitor | Probechem Biochemicals

Chemical Structure : PI4KIIIbeta-IN-10

CAS No.: 1881233-39-1

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PI4KIIIbeta-IN-10 (PI4KIIIβ-IN-10 )

货号: PC-42078Not For Human Use, Lab Use Only.

PI4KIIIβ-IN-10 is a potent and selective type III phosphatidylinositol 4-kinase (PI4KIIIβ) inhibitor with IC50 of 3.6 nM.

规格	价格	库存
5 mg	￥2280	In stock
10 mg	￥3580	In stock
25 mg	￥5580	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

PI4KIIIβ-IN-10 is a potent and selective type III phosphatidylinositol 4-kinase (PI4KIIIβ) inhibitor with IC50 of 3.6 nM.
PI4KIIIβ-IN-10 displays >200-fold selectivity over class I and class III PI3Ks.
PI4KIIIβ-IN-10 shows antiviral activity against hepatitis C virus with IC50 of 1.3 uM, with low cytotoxicity (CC50>32 uM).

物理化学性质&存储条件

分子量	475.581
分子式	C22H25N3O5S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 30 mg/mL
Chemical Name/SMILES	N-(5-(3-(N-(4-hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)pivalamide

参考文献

1. Rutaganira FU, et al. J Med Chem. 2016 Mar 10;59(5):1830-9.

PI4KIIIbeta-IN-10 (PI4KIIIβ-IN-10 )

生物&药学活性

物理化学性质&存储条件

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PI4KIIIbeta-IN-10 (PI4KIIIβ-IN-10 )

生物&药学活性

物理化学性质&存储条件

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