PI3Kδ inhibitor 52 |CAS:1911564-39-0 Probechem Biochemicals

Chemical Structure : PI3Kδ inhibitor 52

CAS No.: 1911564-39-0

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PI3Kδ inhibitor 52 (ZUN64390)

货号: PC-61127Not For Human Use, Lab Use Only.

ZUN64390 is a potent, selective, and efficacious PI3Kδ inhibitor with IC50 of 1.7 nM, >100-fold selectivitity over PI3Kγ/α/β.

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5 mg	￥1880	In stock
25 mg	￥3880	In stock
100 mg	￥9880	In stock
500 mg		Get quote
1 g		Get quote

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生物&药学活性

ZUN64390 is a potent, selective, and efficacious PI3Kδ inhibitor with IC50 of 1.7 nM, >100-fold selectivitity over PI3Kγ/α/β.
ZUN64390 shows potent activity in mouse arthritis models.

物理化学性质&存储条件

分子量	471.444
分子式	C22H20F3N7O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-acetyl-3,3-dimethyl-2-oxopiperazin-1-yl)-4-(4-amino-5-(trifluoromethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl)benzonitrile

参考文献

1. Liu Q, et al. J Med Chem. 2017 Jun 22;60(12):5193-5208.

PI3Kδ inhibitor 52 (ZUN64390)

生物&药学活性

物理化学性质&存储条件

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PI3Kδ inhibitor 52 (ZUN64390)

生物&药学活性

物理化学性质&存储条件

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