PI3K inhibitor X (Pilaralisib analogue) | class I PI3K inhibitor

Chemical Structure : PI3K inhibitor X

CAS No.: 956958-53-5

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PI3K inhibitor X (XL147 analog, Pilaralisib analogue)

货号: PC-42812Not For Human Use, Lab Use Only.

PI3K inhibitor X (XL-147 analog) is a derivative of XL147 that acts as a reversible inhibitor of class I PI3Ks with IC50 of 39, 36, 23 and 383 nM for p110α, δ, γ and β respectively.

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25 mg	￥1480	In stock
50 mg	￥2580	In stock
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PI3K inhibitor X (XL147 analog) is a derivative of XL147 that acts as a reversible inhibitor of class I PI3Ks with IC50 of 39, 36, 23 and 383 nM for p110α, δ, γ and β respectively.
Compound 147 in patent WO2012006552A1.

物理化学性质&存储条件

分子量	448.5208
分子式	C21H16N6O2S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzenesulfonamide, N-[3-(2,1,3-benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methyl-

参考文献

1. Carlos L. Arteaga, et al. Combinations of kinase inhibitors for the treatment of cancer. WO 2012006552 A1.

PI3K inhibitor X (XL147 analog, Pilaralisib analogue)

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物理化学性质&存储条件

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PI3K inhibitor X (XL147 analog, Pilaralisib analogue)

生物&药学活性

物理化学性质&存储条件

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