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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-PI3K-C2γ inhibitor 26
PI3K-C2γ inhibitor 26

Chemical Structure : PI3K-C2γ inhibitor 26

CAS No.: 1620167-04-5

PI3K-C2γ inhibitor 26 (Freitag-26)

货号: PC-23005Not For Human Use, Lab Use Only.

PI3K-C2γ inhibitor 26 is a potent, isoform-selective inhibitor of PI3K-C2γ with IC50 of 340 nM, with no activity against class I and III PI3Ks or a panel of 60 other protein kinases.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PI3K-C2γ inhibitor 26 is a potent, isoform-selective inhibitor of PI3K-C2γ with IC50 of 340 nM, with no activity against class I and III PI3Ks or a panel of 60 other protein kinases.

物理化学性质&存储条件

分子量 401.44
分子式 C18H19N5O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-amino-N-(3-((3,5-dimethoxyphenyl)amino)pyrazin-2-yl)benzenesulfonamide

参考文献

1. Anne Freitag, et al. J Med Chem. 2015 Jan 8;58(1):212-21.

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