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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-PI-3065
PI-3065

Chemical Structure : PI-3065

CAS No.: 955977-50-1

PI-3065 (PI3065;PI 3065)

货号: PC-42925Not For Human Use, Lab Use Only.

PI-3065 is a potent inhibitor of PI3K p110δ with IC50/Ki values of 5/1.5 nM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PI-3065 is a potent inhibitor of PI3K p110δ with IC50/Ki values of 5/1.5 nM respectively.
PI-3065 exhibits less potent activity against p110α, p110β, p110γ with IC50s of 910, 600, >10000 nM.

物理化学性质&存储条件

分子量 506.638
分子式 C27H31FN6OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 50 mM (2.5 mg/mL)

Chemical Name/SMILES

Thieno[3,2-d]pyrimidine, 6-[[4-(cyclopropylmethyl)-1-piperazinyl]methyl]-2-(5-fluoro-1H-indol-4-yl)-4-(4-morpholinyl)-

参考文献

1. Ali K, et al. Nature. 2014 Jun 19;510(7505):407-11.

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