PHT-7.3 | Cnksr1 (Cnk1) inhibitor | Probechem Biochemicals

Chemical Structure : PHT-7.3

CAS No.: 1614225-93-2

加入收藏

PHT-7.3 (Cnksr1 (Cnk1) inhibitor PHT-7.3)

货号: PC-72978Not For Human Use, Lab Use Only.

PHT-7.3 (Cnksr1 (Cnk1) inhibitor PHT-7.3) is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain (Kd=4.7 μM).

规格	价格	库存
5 mg	￥2780	In stock
10 mg	￥4580	In stock
25 mg	￥7580	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

PHT-7.3 (Cnksr1 (Cnk1) inhibitor PHT-7.3) is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain (Kd=4.7 μM).
PHT-7.3 bound selectively to the PH domain of Cnk1, preventing plasma membrane colocalization with mut-KRas.
PHT-7.3 inhibits mut-KRas, but not wild-type KRas cancer cell and tumor growth and signaling.

物理化学性质&存储条件

分子量	433.526
分子式	C24H23N3O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((1,3-dioxan-2-yl)methyl)-2-((4-(p-tolyl)thiazol-2-yl)methyl)phthalazin-1(2H)-one

参考文献

1. Martin Indarte, et al. Cancer Res. 2019 Jun 15;79(12):3100-3111.

PHT-7.3 (Cnksr1 (Cnk1) inhibitor PHT-7.3)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

PHT-7.3 (Cnksr1 (Cnk1) inhibitor PHT-7.3)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.