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首页-小分子抑制剂&激动剂-Tyrosine Kinase-FLT3-PHI-101
PHI-101

Chemical Structure : PHI-101

CAS No.: 2127107-15-5

PHI-101 (Lasmotinib)

货号: PC-24145Not For Human Use, Lab Use Only.

Lasmotinib (PHI-101) is a potent, selectivean orally bioavailable next-generation FLT3 inhibitor, overcomes secondary mutations.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Lasmotinib (PHI-101) is a potent, selectivean orally bioavailable next-generation FLT3 inhibitor, overcomes secondary mutations.

物理化学性质&存储条件

分子量 386.45
分子式 C19H19FN4O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-5-((3-fluorophenyl)ethynyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide

参考文献

1. Park SJ, et al. BMC Cancer. 2022 Jan 3;22(1):28.

2. Sung-Soo Yoon, et al. Blood (2023) 142 (Supplement 1): 4283.

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