Chemical Structure : PHI-101
CAS No.: 2127107-15-5
货号: PC-24145Not For Human Use, Lab Use Only.
Lasmotinib (PHI-101) is a potent, selectivean orally bioavailable next-generation FLT3 inhibitor, potently inhibits FLT3 single activating mutations (ITD or TKD mutants) and has inhibitory activity against FLT3 double (ITD/D835Y or ITD/F691L) and triple (ITD/D835Y/F691L) resistance mutations.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥1180 | In stock | |
| 10 mg | ¥1880 | In stock | |
| 25 mg | ¥3280 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Lasmotinib (PHI-101) is a potent, selectivean orally bioavailable next-generation FLT3 inhibitor, potently inhibits FLT3 single activating mutations (ITD or TKD mutants) and has inhibitory activity against FLT3 double (ITD/D835Y or ITD/F691L) and triple (ITD/D835Y/F691L) resistance mutations.
| 分子量 | 386.45 | |
| 分子式 | C19H19FN4O2S | |
| 外观性状 | Solid | |
| 储存条件 |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-5-((3-fluorophenyl)ethynyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide |
|
1. Park SJ, et al. BMC Cancer. 2022 Jan 3;22(1):28.
2. Sung-Soo Yoon, et al. Blood (2023) 142 (Supplement 1): 4283.
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