PHD2 inhibitor BNS

Chemical Structure : PHD2 inhibitor BNS

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货号: PC-22620Not For Human Use, Lab Use Only.

PHD2 inhibitor BNS is a broad-spectrum 2OG oxygenase inhibitor with IC50 of 0.3 uM, 0.11 uM, 3.4 uM and 0.25 uM for FIH, PHD2, aspartate/asparagine-β-hydroxylase (AspH) and JMJD5, respectively.

规格	价格	库存	数量
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50 mg		Get quote
100 mg		Get quote

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生物&药学活性

PHD2 inhibitor BNS is a broad-spectrum 2OG oxygenase inhibitor with IC50 of 0.3 uM, 0.11 uM, 3.4 uM and 0.25 uM for FIH, PHD2, aspartate/asparagine-β-hydroxylase (AspH) and JMJD5, respectively.

物理化学性质&存储条件

分子量	420.45
分子式	C18H16N2O6S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2,3-Dihydro-3-hydroxy-2-[[2-[(2-naphthalenylmethyl)sulfonyl]acetyl]imino]-4-thiazoleacetic acid

参考文献

1. Thomas P Corner, et al. Chem Sci. 2023 Oct 27;14(43):12098-12120.