PH002 | ApoE4 inhibitor | Probechem Biochemicals

Chemical Structure : PH002

CAS No.: 1311174-68-1

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PH002 (PH-002)

货号: PC-63439Not For Human Use, Lab Use Only.

PH002 is a small-molecule structure corrector significantly decreased ApoE4 fragment levels in ApoE4/4-hiPSC-derived neurons, increases GABAergic neuron numbers and GAD67 levels, reduces p-tau levels, and decreases Aβ40 and Aβ42 production and/or secretion.

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5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3580	In stock
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100 mg		Get quote

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生物&药学活性

PH002 is a small-molecule structure corrector significantly decreased ApoE4 fragment levels in ApoE4/4-hiPSC-derived neurons, increases GABAergic neuron numbers and GAD67 levels, reduces p-tau levels, and decreases Aβ40 and Aβ42 production and/or secretion.

物理化学性质&存储条件

分子量	491.58
分子式	C27H33N5O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[[4-[[2-(3,4-Dihydro-3-methyl-4-oxo-1-phthalazinyl)acetyl]amino]phenyl]methyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester

参考文献

1. Wang C, et al. Nat Med. 2018 Apr 9. doi: 10.1038/s41591-018-0004-z.

PH002 (PH-002)

生物&药学活性

物理化学性质&存储条件

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PH002 (PH-002)

生物&药学活性

物理化学性质&存储条件

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