PGC-1α inhibitor C80

Chemical Structure : PGC-1α inhibitor C80

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货号: PC-62697Not For Human Use, Lab Use Only.

PGC-1α inhibitor C80 is a potent PGC-1α inhibitor, activates PGC-1α acetylation with AC50 of 3.1 uM, induces Pck1 and G6pc expression with AC50 of 11.9 uM and 12.8 uM, reduces glucose production in hepatocytes.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

PGC-1α inhibitor C80 is a potent PGC-1α inhibitor, activates PGC-1α acetylation with AC50 of 3.1 uM, induces Pck1 and G6pc expression with AC50 of 11.9 uM and 12.8 uM, reduces glucose production in hepatocytes.

物理化学性质&存储条件

分子量	380.532
分子式	C24H32N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(tert-butyl(4-methylbenzyl)amino)-3-((3-methyl-1H-indol-4-yl)oxy)propan-2-ol

参考文献

1. Sharabi K, et al. Cell. 2017 Mar 23;169(1):148-160.e15.