PG3d | Caspase-6 inhibitor | Probechem Biochemicals

Chemical Structure : PG3d

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PG3d (Caspase-6 inhibitor PG3d)

货号: PC-73049Not For Human Use, Lab Use Only.

PG3d (Caspase-6 inhibitor PG3d) is a cell-active, allosteric and irreversible, non-competitive Caspase-6 inhibitor.

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生物&药学活性

PG3d (Caspase-6 inhibitor PG3d) is a cell-active, allosteric and irreversible, non-competitive Caspase-6 inhibitor.
PG3d preferentially inhibits the cleavage of protein over peptide substrates both with purified proteins and in live cells.
PG3d prevents the C6 (Caspase-6)-HTT interaction and prevents mHTT1-586 mediated activation of procaspase-6.
PG3d specifically inhibits the cleavage of protein, but not peptide substrates of Caspase-6.

物理化学性质&存储条件

分子量	303.317
分子式	C19H13NO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-Benzyl-4-hydroxy-2-(phenylethynyl)-6H-1,3-oxazin-6-one

参考文献

1. Ehrnhoefer DE, et al. Cell Chem Biol. 2019 Sep 19;26(9):1295-1305.e6.

PG3d (Caspase-6 inhibitor PG3d)

生物&药学活性

物理化学性质&存储条件

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PG3d (Caspase-6 inhibitor PG3d)

生物&药学活性

物理化学性质&存储条件

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