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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-PG01037
PG01037

Chemical Structure : PG01037

CAS No.: 790658-27-4

PG01037 (PG 01037)

货号: PC-20862Not For Human Use, Lab Use Only.

PG01037 is a potent selective dopamine D3 receptor antagonist with binding Ki of 0.7 nM, displays 133- and 540-fold selectivity over D2 and D4 receptors, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PG01037 is a potent selective dopamine D3 receptor antagonist with binding Ki of 0.7 nM, displays 133- and 540-fold selectivity over D2 and D4 receptors, respectively.

物理化学性质&存储条件

分子量 481.42
分子式 C26H26Cl2N4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(NC/C=C/CN1CCN(C2=CC=CC(Cl)=C2Cl)CC1)C3=CC=C(C4=NC=CC=C4)C=C3

参考文献

1. Grundt P, et al. J Med Chem. 2007 Aug 23;50(17):4135-46.

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