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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-E3 Ubiquitin Ligase-PFI-E3H1
PFI-E3H1

Chemical Structure : PFI-E3H1

CAS No.: 2910887-73-7

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PFI-E3H1

货号: PC-22418Not For Human Use, Lab Use Only.

PFI-E3H1 is a potent, selective chemical handle of Gid4 subunit of the human E3 ligase CTLH degradation complex with IC50 of 2.5 uM in NanoBRET assay measuring the Gid4/MPGLWKS interaction.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PFI-E3H1 is a potent, selective chemical handle of Gid4 subunit of the human E3 ligase CTLH degradation complex with IC50 of 2.5 uM in NanoBRET assay measuring the Gid4/MPGLWKS interaction.

物理化学性质&存储条件

分子量 362.48
分子式 C22H26N4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Acetamide, N-[cis-4-(1H-benzimidazol-2-yl)cyclohexyl]-2-[[(1R)-1-phenylethyl]amino]-

参考文献

1. Yazdi AK, et al. RSC Med Chem. 2024 Mar 5;15(3):1066-1071.

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