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PFI-4

Chemical Structure : PFI-4

CAS No.: 900305-37-5

PFI-4 (PFI4, BRPF1 inhibitor PFI-4)

货号: PC-45507Not For Human Use, Lab Use Only.

PFI-4 is a potent, selective inhibitor of the BRPF1 bromodomain with pIC50 of 7.3.

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25 mg ¥1380 In stock
50 mg ¥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PFI-4 is a potent, selective inhibitor of the BRPF1 bromodomain with pIC50 of 7.3.
PFI-4 exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4.

物理化学性质&存储条件

分子量 380.4402
分子式 C21H24N4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 26 mg/mL

Chemical Name/SMILES

Benzamide, N-[2,3-dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxy-

参考文献

1. Demont EH, et al. ACS Med Chem Lett. 2014 Sep 10;5(11):1190-5.

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