PF-6808472 (XO44) |CAS:2088112-70-1 Probechem Biochemicals

Chemical Structure : PF-6808472

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PF-6808472 (XO44)

货号: PC-62860Not For Human Use, Lab Use Only.

PF-6808472 (XO44) is a sulfonyl fluoride chemical probe that covalently labels a broad swath of the intracellular kinome with high efficiency.

规格	价格	库存	数量
25 mg		Get quote
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100 mg		Get quote

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生物&药学活性

PF-6808472 (XO44) is a sulfonyl fluoride chemical probe that covalently labels a broad swath of the intracellular kinome with high efficiency.
PF-6808472 (XO44) covalently modifies up to 133 endogenous kinases, efficiently competes with high intracellular concentrations of ATP.
PF-6808472 (XO44) an useful tool in demanding chemoproteomic applications.

物理化学性质&存储条件

分子量	538.602
分子式	C25H27FN8O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-{4-[4-(5-Cyclopropyl-1H-pyrazol-3-ylamino)-6-prop-2-ynylcarbamoyl-pyrimidin-2-yl]-piperazin-1-ylmethyl}-benzenesulfonyl fluoride

参考文献

1. Zhao Q, et al. J Am Chem Soc. 2017 Jan 18;139(2):680-685.

PF-6808472 (XO44)

生物&药学活性

物理化学性质&存储条件

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PF-6808472 (XO44)

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