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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-TRP Channel-PF-4840154
PF-4840154

Chemical Structure : PF-4840154

CAS No.: 1332708-14-1

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PF-4840154 (PF4840154)

货号: PC-45556Not For Human Use, Lab Use Only.

PF-4840154 is a potent, selective agonist of the rat (EC50=97 nM) and human (EC50=23 nM) TRPA1 channel.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PF-4840154 is a potent, selective agonist of the rat (EC50=97 nM) and human (EC50=23 nM) TRPA1 channel.
PF-4840154 elicitsTRPA1-mediated nocifensive behaviour in mouse.

物理化学性质&存储条件

分子量 466.6189
分子式 C26H38N6O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-Pyrimidinecarboxamide, 4-[(2-methylpropyl)amino]-N-(phenylmethyl)-2-[4-[(tetrahydro-2H-pyran-3-yl)methyl]-1-piperazinyl]-

参考文献

1. Ryckmans T, et al. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4857-9.

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