PF-4181366 (PF-04181366) | PDE9A inhibitor | Probechem Biochemicals

Chemical Structure : PF-4181366

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PF-4181366 (PF-04181366, PF04181366, PF4181366)

货号: PC-60206Not For Human Use, Lab Use Only.

PF-4181366 (PF-04181366) is a potent, selective, brain penetrant PDE9A inhibitor with IC50 of 1.8 nM.

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生物&药学活性

PF-4181366 (PF-04181366) is a potent, selective, brain penetrant PDE9A inhibitor with IC50 of 1.8 nM.
PF-4181366 (PF-04181366) displays >25-fold selectivity over other PDEs.

物理化学性质&存储条件

分子量	429.53
分子式	C24H27N7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1-cyclopentyl-1,5-dihydro-6-((3S,4S)-4-methyl-1-(6-quinoxalinylmethyl)-3-pyrrolidinyl)-

参考文献

1. Verhoest PR, et al. J Med Chem. 2009 Dec 24;52(24):7946-9.

PF-4181366 (PF-04181366, PF04181366, PF4181366)

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物理化学性质&存储条件

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PF-4181366 (PF-04181366, PF04181366, PF4181366)

生物&药学活性

物理化学性质&存储条件

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