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PF-06928215

Chemical Structure : PF-06928215

CAS No.: 2378173-15-8

PF-06928215 (PF 06928215, PF06928215)

货号: PC-61340Not For Human Use, Lab Use Only.

PF-06928215 (PF06928215) is a high affinity Cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 200 nM, IC50 of 4.9 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PF-06928215 (PF06928215) is a high affinity Cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 200 nM, IC50 of 4.9 uM.

物理化学性质&存储条件

分子量 380.404
分子式 C20H20N4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,2S)-2-(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamido)cyclohexane-1-carboxylic acid

参考文献

1. Hall J, et al. PLoS One. 2017 Sep 21;12(9):e0184843.

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