PF-06807656 |CAS:2213468-04-1 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-PF-06807656

Chemical Structure : PF-06807656

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PF-06807656 (PF06807656)

货号: PC-63348Not For Human Use, Lab Use Only.

PF-06807656 is a potent, selective renal outer medullary potassium channel (ROMK, Kir1.1a) inhibitor with IC50 of 61 nM for hROMK in patch-clamp assays.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PF-06807656 is a potent, selective renal outer medullary potassium channel (ROMK, Kir1.1a) inhibitor with IC50 of 61 nM for hROMK in patch-clamp assays.
PF-06807656 is highly selective for inhibition of human over rat ROMK and to be insensitive to the N171D pore mutation.

物理化学性质&存储条件

分子量	449.91
分子式	C19H20ClN5O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(N-(4-chlorophenyl)sulfamoyl)-4-methoxy-N-(1-(2-methyl-2H-1,2,3-triazol-4-yl)ethyl)benzamide

参考文献

1. Sammons MF, et al. ACS Med Chem Lett. 2018 Jan 19;9(2):125-130.

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PF-06807656 (PF06807656)

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物理化学性质&存储条件

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PF-06807656 (PF06807656)

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物理化学性质&存储条件

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