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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-PF-06669571
PF-06669571

Chemical Structure : PF-06669571

CAS No.: 3034857-88-7

PF-06669571 (Raxlaprazine Etomoxil, PF-6669571)

货号: PC-62632Not For Human Use, Lab Use Only.

Raxlaprazine Etomoxil (PF-06669571, PF-6669571) is a novel dopamine D1 receptor (D1R) partial agonist with Ki of 10 nM, demonstrates efficacy in pre-clinical models of Parkinson’s disease symptoms.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Raxlaprazine Etomoxil (PF-06669571, PF-6669571) is a novel dopamine D1 receptor (D1R) partial agonist with Ki of 10 nM, demonstrates efficacy in pre-clinical models of Parkinson’s disease symptoms.

    物理化学性质&存储条件

    分子量 471.47
    分子式 C23H36Cl2N4O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Urea, N′-[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N-(ethoxymethyl)-N-methyl-

    参考文献

    1. Gurrell R, et al. Clin Drug Investig. 2018 Feb 24. doi: 10.1007/s40261-018-0632-6.

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