PF-06426779 |CAS:1817628-40-2 Probechem Biochemicals

Chemical Structure : PF-06426779

加入收藏

PF-06426779 (PF06426779)

货号: PC-35553Not For Human Use, Lab Use Only.

PF-06426779 (PF06426779) is a potent, selective IRAK4 inhibitor with IC50 of 1 nM against full-length IRAK4 kinase and cell-based IC50 of 12 nM.

规格	价格	库存	数量
5 mg		Get quote
10 mg		Get quote
25 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

PF-06426779 (PF06426779) is a potent, selective IRAK4 inhibitor with IC50 of 1 nM against full-length IRAK4 kinase and cell-based IC50 of 12 nM.
PF-06426779 displays excellent selectivity against the human kinome, and >100-fold selectivity for IRAK4 over IRAK1.

物理化学性质&存储条件

分子量	347.346
分子式	C17H18FN3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(((2S,3S,4S)-4-Fluoro-3-methyl-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide

参考文献

1. De Nardo D, et al. J Biol Chem. 2018 Aug 3. pii: jbc.RA118.003314.

2. Lee KL, et al. J Med Chem. 2017 Jul 13;60(13):5521-5542.

PF-06426779 (PF06426779)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

PF-06426779 (PF06426779)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.