PF-05212377 |CAS:1226793-34-5 Probechem Biochemicals

Chemical Structure : PF-05212377

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PF-05212377 (SAM-760;PF 5212377)

货号: PC-35004Not For Human Use, Lab Use Only.

PF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with Ki of 0.32 nM (human 5HT6), shows potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease.

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生物&药学活性

PF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with Ki of 0.32 nM (human 5HT6), shows potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease.

物理化学性质&存储条件

分子量	356.444
分子式	C18H20N4O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-methyl-1-(phenylsulfonyl)-4-(piperazin-1-yl)-1H-benzo[d]imidazole

参考文献

1. Fullerton T, et al. Alzheimers Res Ther. 2018 Apr 5;10(1):38.

2. Fullerton T, et al. Alzheimers Res Ther. 2018 Apr 5;10(1):38.

PF-05212377 (SAM-760;PF 5212377)

生物&药学活性

物理化学性质&存储条件

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PF-05212377 (SAM-760;PF 5212377)

生物&药学活性

物理化学性质&存储条件

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