PF-04958242 (Pesampator) |CAS:1258963-59-5 Probechem Biochemicals

Chemical Structure : PF-04958242

CAS No.: 1258963-59-5

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PF-04958242 (Pesampator, PF04958242)

货号: PC-61864Not For Human Use, Lab Use Only.

PF-04958242 (Pesampator) is a novel potent, selctive, and orally-active AMPA receptor (AMPAR) positive allosteric modulator (PAM) with Ki of 170 nM, EC50 of 370 nM.

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5 mg	￥2280	In stock
10 mg	￥3780	In stock
25 mg	￥5980	In stock
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100 mg		Get quote

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生物&药学活性

PF-04958242 (Pesampator) is a novel potent, selctive, and orally-active AMPA receptor (AMPAR) positive allosteric modulator (PAM) with Ki of 170 nM, EC50 of 370 nM.
PF-04958242 (Pesampator) is under development for the treatment of cognitive symptoms in schizophrenia.

物理化学性质&存储条件

分子量	392.49
分子式	C18H20N2O4S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((3S,4S)-4-(4-(5-cyano-2-thienyl)phenoxy)tetrahydro-3-furanyl)-2-propanesulfonamide

参考文献

1. Shaffer CL, et al. J Med Chem. 2015 May 28;58(10):4291-308.

2. Ranganathan M, et al. Mol Psychiatry. 2017 Feb 28. doi: 10.1038/mp.2017.6.

PF-04958242 (Pesampator, PF04958242)

生物&药学活性

物理化学性质&存储条件

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PF-04958242 (Pesampator, PF04958242)

生物&药学活性

物理化学性质&存储条件

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