PF-04929113 Mesylate |CAS:1173111-67-5 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Heat Shock Protein (HSP)-PF-04929113 Mesylate

Chemical Structure : PF-04929113 Mesylate

CAS No.: 1173111-67-5

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PF-04929113 Mesylate (SNX-5422 Mesylate;PF04929113 Mesylate;SNX5422 Mesylate)

货号: PC-42460Not For Human Use, Lab Use Only.

The prodrug of PF-04928473 (SNX-2112), a potent, orally bioavailable HSP90 inhibitor.

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10 mg	￥1880	In stock
25 mg	￥2980	In stock
50 mg	￥4880	In stock
100 mg		Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

The prodrug of PF-04928473 (SNX-2112), a potent, orally bioavailable HSP90 inhibitor, inhibits several signaling pathways and induces apoptosis in CRPC LNCaP tumors in vivo.

物理化学性质&存储条件

分子量	617.6377
分子式	C26H34F3N5O7S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Glycine, trans-4-[[2-(aminocarbonyl)-5-[4,5,6,7-tetrahydro-6,6-dimethyl-4-oxo-3-(trifluoromethyl)-1H-indazol-1-yl]phenyl]amino]cyclohexyl ester, methanesulfonate (1:1)

参考文献

1. Lamoureux F, et al. Clin Cancer Res. 2011 Jul 15;17(14):4916.

2. Rajan A, et al. Clin Cancer Res. 2011 Nov 1;17(21):6831-9.

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PF-04929113 Mesylate (SNX-5422 Mesylate;PF04929113 Mesylate;SNX5422 Mesylate)

生物&药学活性

物理化学性质&存储条件

参考文献

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PF-04929113 Mesylate (SNX-5422 Mesylate;PF04929113 Mesylate;SNX5422 Mesylate)

生物&药学活性

物理化学性质&存储条件

参考文献

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