PF-04895162 | Probechem Biochemicals

Chemical Structure : PF-04895162

加入收藏

PF-04895162 (ICA-105665;PF 04895162;ICA105665;PF 4895162 )

货号: PC-36142Not For Human Use, Lab Use Only.

PF-04895162 (ICA-105665, PF 4895162) is an orally available agonist of neuronal Kv7 potassium channel, opens Kv7.2/7.3 and Kv7.3/7.5 potassium channels, also known as KCNQ2/3 and KCNQ3/5 channels.

规格	价格	库存	数量
25 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

PF-04895162 (ICA-105665, PF 4895162) is an orally available agonist of neuronal Kv7 potassium channel, opens Kv7.2/7.3 and Kv7.3/7.5 potassium channels, also known as KCNQ2/3 and KCNQ3/5 channels.
PF-04895162 (ICA-105665 has demonstrated broad spectrum antiseizure activity in multiple animal models including maximal electroshock, 6 Hz seizures, pentylenetetrazole, and electrical kindling at doses from <1 to 5 mg/kg.

物理化学性质&存储条件

分子量	355.345
分子式	C19H15F2N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-cyclopropyl-7-fluoro-4-oxoquinazolin-3(4H)-yl)-2-(4-fluorophenyl)ethanamide

参考文献

1. Kasteleijn-Nolst Trenité DG, et al. Epilepsia. 2013 Aug;54(8):1437-43.

2. Aleo MD, et al. Pharmacol Res Perspect. 2019 Feb;7(1):e00467.

3. Bialer M, et al. Epilepsy Res. 2013 Jan;103(1):2-30.

4. Roeloffs R, et al. J Pharmacol Exp Ther. 2008 Sep;326(3):818-28.

PF-04895162 (ICA-105665;PF 04895162;ICA105665;PF 4895162 )

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

PF-04895162 (ICA-105665;PF 04895162;ICA105665;PF 4895162 )

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.