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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-PF-04701475
PF-04701475

Chemical Structure : PF-04701475

CAS No.: 1488407-52-8

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PF-04701475 (PF04701475)

货号: PC-61705Not For Human Use, Lab Use Only.

PF-04701475 is a potent positive allosteric modulator of AMPA receptor with EC50 of 123 nM, a prototype used to explore AMPAR-mediated pharmacology in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    PF-04701475 is a potent positive allosteric modulator of AMPA receptor with EC50 of 123 nM, a prototype used to explore AMPAR-mediated pharmacology in vivo.

    物理化学性质&存储条件

    分子量 369.45
    分子式 C17H24FN3O3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-[[(5S)-3-[3-Fluoro-4-(1-pyrrolidinyl)phenyl]-4,5-dihydro-5-isoxazolyl]methyl]-2-propanesulfonamide

    参考文献

    1. Patel NC, et al. J Med Chem. 2013 Nov 27;56(22):9180-91.

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