PF-03382792 | 5-HT4 agonist | Probechem Biochemicals

Chemical Structure : PF-03382792

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PF-03382792 (PF-3382792)

货号: PC-61883Not For Human Use, Lab Use Only.

PF-03382792 is a potent, brain penetrant 5-HT4 partial agonist with Ki of 2.7 nM and an EC50 of 0.9 nM for 5-HT4d, produces moderate increases in cortical Ach in the rat prefrontal cortex.

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PF-03382792 is a potent, brain penetrant 5-HT4 partial agonist with Ki of 2.7 nM and an EC50 of 0.9 nM for 5-HT4d, produces moderate increases in cortical Ach in the rat prefrontal cortex.

物理化学性质&存储条件

分子量	433.52
分子式	C23H32FN3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Indole-1-carboxamide, 6-fluoro-2,3-dihydro-3,3-dimethyl-2-oxo-N-((1-((tetrahydro-4-hydroxy-2H-pyran-4-yl)methyl)-4-piperidinyl)methyl)-

参考文献

1. Michael A Brodney, et al. J Med Chem. 2012 Nov 8;55(21):9240-54.

PF-03382792 (PF-3382792)

生物&药学活性

物理化学性质&存储条件

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PF-03382792 (PF-3382792)

生物&药学活性

物理化学性质&存储条件

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