PF-02575799 |CAS:863491-70-7 Probechem Biochemicals

Chemical Structure : PF-02575799

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PF-02575799 (PF02575799)

货号: PC-63288Not For Human Use, Lab Use Only.

PF-02575799 is a highly potent microsomal triglyceride transfer protein (MTP) inhibitor with IC50 of 0.77 nM.

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生物&药学活性

PF-02575799 is a highly potent microsomal triglyceride transfer protein (MTP) inhibitor with IC50 of 0.77 nM; produces appreciable triglyceride effects at its minimally effective dose (10 mg/kg), significantly increases alanine transaminase at 100 mg/kg.

物理化学性质&存储条件

分子量	680.78
分子式	C42H37FN4O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[(1S)-2-[[(4-Fluorophenyl)methyl]methylamino]-2-oxo-1-phenylethyl]-2-[[[4'-(1-methylethoxy)[1,1'-biphenyl]-2-yl]carbonyl]amino]-6-quinolinecarboxamide

参考文献

1. Robinson RP, et al. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4150-4.

PF-02575799 (PF02575799)

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物理化学性质&存储条件

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PF-02575799 (PF02575799)

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物理化学性质&存储条件

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